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Super-enhancer-mediated core regulatory circuitry in human cancer
Super-enhancers (SEs) are congregated enhancer clusters with high level of loading of transcription factors (TFs), cofactors and epigenetic modifications. Through direct co-occupancy at their own SEs as well as each other’s, a small set of so called “master” TFs form interconnected core regulatory c...
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| Veröffentlicht in: | Comput Struct Biotechnol J |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Research Network of Computational and Structural Biotechnology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138668/ https://ncbi.nlm.nih.gov/pubmed/34093993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.006 |
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