High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

The KIR (killer-cell immunoglobulin-like receptor) region is characterized by structural variation and high sequence similarity among genes, imposing technical difficulties for analysis. We undertook the most comprehensive study to date of KIR genetic diversity in a large population sample, applying...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Amorim, Leonardo M., Augusto, Danillo G., Nemat-Gorgani, Neda, Montero-Martin, Gonzalo, Marin, Wesley M., Shams, Hengameh, Dandekar, Ravi, Caillier, Stacy, Parham, Peter, Fernández-Viña, Marcelo A., Oksenberg, Jorge R., Norman, Paul J., Hollenbach, Jill A.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137979/
https://ncbi.nlm.nih.gov/pubmed/34025673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.674778
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