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Killer-cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson’s Disease

Immune dysfunction plays a role in the development of Parkinson’s disease (PD). Natural killer (NK) cells regulate immune functions and are modulated by killer cell immunoglobulin-like receptors (KIR). KIR are expressed on the surface of NK cells and interact with human leukocyte antigen (HLA) class...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Anderson, Kirsten M., Augusto, Danillo G., Dandekar, Ravi, Shams, Hengameh, Zhao, Chao, Yusufali, Tasneem, Montero-Martín, Gonzalo, Marin, Wesley M., Nemat-Gorgani, Neda, Creary, Lisa E., Caillier, Stacy, Mofrad, Mohammad R. K., Parham, Peter, Fernández-Viña, Marcelo, Oksenberg, Jorge R., Norman, Paul J., Hollenbach, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484130/
https://ncbi.nlm.nih.gov/pubmed/32709660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000144
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