A splice acceptor variant in HLA‐DRA affects the conformation and cellular localization of the class II DR alpha‐chain

Class II human leucocyte antigen (HLA) proteins are involved in the immune response by presenting pathogen‐derived peptides to CD4(+) T lymphocytes. At the molecular level, they are constituted by α/β‐heterodimers on the surface of professional antigen‐presenting cells. Here, we report that the acce...

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Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Didonna, Alessandro, Damotte, Vincent, Shams, Hengameh, Matsunaga, Atsuko, Caillier, Stacy J., Dandekar, Ravi, Misra, Maneesh K., Mofrad, Mohammad R. K., Oksenberg, Jorge R., Hollenbach, Jill A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808164/
https://ncbi.nlm.nih.gov/pubmed/32986852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13273
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