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Structure based selection of Human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis
Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous metabolites. We performed virtual screening of the com...
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| 發表在: | Genes Immun |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054566/ https://ncbi.nlm.nih.gov/pubmed/29362509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-017-0009-5 |
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