Deconstruction of HLA-DRB1*04:01:01 and HLA-DRB1*15:01:01 class II haplotypes using next generation sequencing in European Americans with multiple sclerosis.

BACKGROUND: The association between HLA-DRB1*15:01 with multiple sclerosis (MS) susceptibility is well established but the contribution of the tightly associated HLA-DRB5*01:01 allele has not yet been completely ascertained. Similarly, the effects of HLA-DRB1*04:01 alleles and haplotypes, defined at...

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Bibliografiska uppgifter
I publikationen:Mult Scler
Huvudupphovsmän: Creary, Lisa E., Mallempati, Kalyan C., Gangavarapu, Sridevi, Caillier, Stacy J., Oksenberg, Jorge R., Fernández-Viňa, Marcelo A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365219/
https://ncbi.nlm.nih.gov/pubmed/29683085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458518770019
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