HLA-DRB1*04:01 restricted T cells in blood and synovial fluid of RA patients

OBJECTIVE: ACPA-positive RA is associated with distinct HLA-DR alleles and with antibodies targeting citrullinated α-enolase. We screened α-enolase for tentative T cell epitopes and focused the present study on aa326–340. Both the frequency and quality of T cell responses were studied in blood and s...

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Publicat a:J Autoimmun
Autors principals: Pieper, Jennifer, James, Eddie, Dubnovitsky, Anatoly, Gerstner, Christina, Rieck, Mary, Sandin, Charlotta, Gebe, John A, Klareskog, Lars, Achour, Adnane, Buckner, Jane H, Malmström, Vivianne
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259322/
https://ncbi.nlm.nih.gov/pubmed/29853344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.04.004
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