Citrulline specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy

OBJECTIVE: Rheumatoid arthritis is thought to be a T cell mediated disease, based on its strong association with HLA class II alleles, clinical responsiveness to T cell directed therapies and the presence of CD4 T cells in rheumatoid joints. The presence of ACPA in RA serum and the association of th...

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Pubblicato in:Arthritis Rheumatol
Autori principali: James, Eddie, Rieck, Mary, Pieper, Jennifer, Gebe, John A., Yue, Betty B., Tatum, Megan, Peda, Melissa, Sandin, Charlotta, Klareskog, Lars, Malmström, Vivianne, Buckner, Jane H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248674/
https://ncbi.nlm.nih.gov/pubmed/24665079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38637
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