Identification and functional characterization of T cells reactive to citrullinated-vimentin in HLA-DRB1*0401 humanized mice and RA patients

OBJECTIVE: Antibodies towards the citrullinated form of the synovial antigen vimentin are specific for rheumatoid arthritis (RA) and associated with HLADRB1*0401. This suggests that T cells specific for peptides derived from citrullinated-vimentin presented in the context of HLA-DRB1*0401 may contri...

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Detalhes bibliográficos
Main Authors: Snir, Omri, Rieck, Mary, Gebe, John A., Yue, Betty B., Rawlings, Crystal A., Nepom, Gerald, Malmström, Vivianne, Buckner, Jane H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174345/
https://ncbi.nlm.nih.gov/pubmed/21567378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30445
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