In vitro and ex vivo functional characterization of human HLA-DRB1∗04 restricted T cell receptors

Recent advances in single-cell sequencing technologies enable the generation of large-scale data sets of paired TCR sequences from patients with autoimmune disease. Methods to validate and characterize patient-derived TCR data are needed, as well as relevant model systems that can support the develo...

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Vydáno v:J Transl Autoimmun
Hlavní autoři: Boddul, Sanjaykumar V., Sharma, Ravi Kumar, Dubnovitsky, Anatoly, Raposo, Bruno, Gerstner, Christina, Shen, Yunbing, Iyer, Vaishnavi Srinivasan, Kasza, Zsolt, Kwok, William W., Winkler, Aaron R., Klareskog, Lars, Malmström, Vivianne, Bettini, Maria, Wermeling, Fredrik
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980064/
https://ncbi.nlm.nih.gov/pubmed/33768201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2021.100087
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