In vitro and ex vivo functional characterization of human HLA-DRB1∗04 restricted T cell receptors

Recent advances in single-cell sequencing technologies enable the generation of large-scale data sets of paired TCR sequences from patients with autoimmune disease. Methods to validate and characterize patient-derived TCR data are needed, as well as relevant model systems that can support the develo...

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Detalhes bibliográficos
Publicado no:J Transl Autoimmun
Main Authors: Boddul, Sanjaykumar V., Sharma, Ravi Kumar, Dubnovitsky, Anatoly, Raposo, Bruno, Gerstner, Christina, Shen, Yunbing, Iyer, Vaishnavi Srinivasan, Kasza, Zsolt, Kwok, William W., Winkler, Aaron R., Klareskog, Lars, Malmström, Vivianne, Bettini, Maria, Wermeling, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980064/
https://ncbi.nlm.nih.gov/pubmed/33768201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2021.100087
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