In vitro and ex vivo functional characterization of human HLA-DRB1∗04 restricted T cell receptors

Recent advances in single-cell sequencing technologies enable the generation of large-scale data sets of paired TCR sequences from patients with autoimmune disease. Methods to validate and characterize patient-derived TCR data are needed, as well as relevant model systems that can support the develo...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Transl Autoimmun
Huvudupphovsmän: Boddul, Sanjaykumar V., Sharma, Ravi Kumar, Dubnovitsky, Anatoly, Raposo, Bruno, Gerstner, Christina, Shen, Yunbing, Iyer, Vaishnavi Srinivasan, Kasza, Zsolt, Kwok, William W., Winkler, Aaron R., Klareskog, Lars, Malmström, Vivianne, Bettini, Maria, Wermeling, Fredrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Research paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980064/
https://ncbi.nlm.nih.gov/pubmed/33768201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2021.100087
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