IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints

Neutrophils are the most abundant immune cells found in actively inflamed joints of patients with rheumatoid arthritis (RA), and most animal models for RA depend on neutrophils for the induction of joint inflammation. Exogenous IL-4 and IL-13 protect mice from antibody-mediated joint inflammation, a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Panda, Sudeepta Kumar, Wigerblad, Gustaf, Jiang, Long, Jiménez-Andrade, Yanek, Iyer, Vaishnavi Srinivasan, Shen, Yunbing, Boddul, Sanjaykumar V., Guerreiro-Cacais, André Ortlieb, Raposo, Bruno, Kasza, Zsolt, Wermeling, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022208/
https://ncbi.nlm.nih.gov/pubmed/31980518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914186117
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