Designing custom CRISPR libraries for hypothesis-driven drug target discovery

Over the last decade Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) has been developed into a potent molecular biology tool used to rapidly modify genes or their expression in a multitude of ways. In parallel, CRISPR-based screening approaches have been developed as powerful disc...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Iyer, Vaishnavi Srinivasan, Jiang, Long, Shen, Yunbing, Boddul, Sanjaykumar V., Panda, Sudeepta Kumar, Kasza, Zsolt, Schmierer, Bernhard, Wermeling, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479249/
https://ncbi.nlm.nih.gov/pubmed/32952937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.08.009
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