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A splice acceptor variant in HLA‐DRA affects the conformation and cellular localization of the class II DR alpha‐chain

Class II human leucocyte antigen (HLA) proteins are involved in the immune response by presenting pathogen‐derived peptides to CD4(+) T lymphocytes. At the molecular level, they are constituted by α/β‐heterodimers on the surface of professional antigen‐presenting cells. Here, we report that the acce...

詳細記述

保存先:
書誌詳細
出版年:Immunology
主要な著者: Didonna, Alessandro, Damotte, Vincent, Shams, Hengameh, Matsunaga, Atsuko, Caillier, Stacy J., Dandekar, Ravi, Misra, Maneesh K., Mofrad, Mohammad R. K., Oksenberg, Jorge R., Hollenbach, Jill A.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808164/
https://ncbi.nlm.nih.gov/pubmed/32986852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13273
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