High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

The KIR (killer-cell immunoglobulin-like receptor) region is characterized by structural variation and high sequence similarity among genes, imposing technical difficulties for analysis. We undertook the most comprehensive study to date of KIR genetic diversity in a large population sample, applying...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Amorim, Leonardo M., Augusto, Danillo G., Nemat-Gorgani, Neda, Montero-Martin, Gonzalo, Marin, Wesley M., Shams, Hengameh, Dandekar, Ravi, Caillier, Stacy, Parham, Peter, Fernández-Viña, Marcelo A., Oksenberg, Jorge R., Norman, Paul J., Hollenbach, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137979/
https://ncbi.nlm.nih.gov/pubmed/34025673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.674778
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