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Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region

The killer-cell immunoglobulin-like receptor (KIR) region comprises a fast-evolving family of genes that encode receptors for natural killer (NK) cells and have crucial role in host defense. Evolution of KIR was examined in the context of the human genome. Gene-content diversity and single nucleotid...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Augusto, Danillo G., Norman, Paul J., Dandekar, Ravi, Hollenbach, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533848/
https://ncbi.nlm.nih.gov/pubmed/31156615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00989
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