Allele-Level KIR Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations

The killer-cell immunoglobulin-like receptor (KIR) genes regulate natural killer cell activity, influencing predisposition to immune mediated disease, and affecting hematopoietic stem cell transplantation (HSCT) outcome. Owing to the complexity of the KIR locus, with extensive gene copy number varia...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Wagner, Ines, Schefzyk, Daniel, Pruschke, Jens, Schöfl, Gerhard, Schöne, Bianca, Gruber, Nicole, Lang, Kathrin, Hofmann, Jan, Gnahm, Christine, Heyn, Bianca, Marin, Wesley M., Dandekar, Ravi, Hollenbach, Jill A., Schetelig, Johannes, Pingel, Julia, Norman, Paul J., Sauter, Jürgen, Schmidt, Alexander H., Lange, Vinzenz
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288436/
https://ncbi.nlm.nih.gov/pubmed/30564239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02843
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires