Allele-Level KIR Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations

The killer-cell immunoglobulin-like receptor (KIR) genes regulate natural killer cell activity, influencing predisposition to immune mediated disease, and affecting hematopoietic stem cell transplantation (HSCT) outcome. Owing to the complexity of the KIR locus, with extensive gene copy number varia...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Wagner, Ines, Schefzyk, Daniel, Pruschke, Jens, Schöfl, Gerhard, Schöne, Bianca, Gruber, Nicole, Lang, Kathrin, Hofmann, Jan, Gnahm, Christine, Heyn, Bianca, Marin, Wesley M., Dandekar, Ravi, Hollenbach, Jill A., Schetelig, Johannes, Pingel, Julia, Norman, Paul J., Sauter, Jürgen, Schmidt, Alexander H., Lange, Vinzenz
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288436/
https://ncbi.nlm.nih.gov/pubmed/30564239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02843
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