High-Throughput MICA/B Genotyping of Over Two Million Samples: Workflow and Allele Frequencies

MICA and MICB are ligands of the NKG2D receptor and thereby influence NK and T cell activity. MICA/B gene polymorphisms, expression levels and the amount of soluble MICA/B in the serum have been linked to autoimmune diseases, infections, and cancer. In hematopoietic stem cell transplantation, MICA m...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Klussmeier, Anja, Massalski, Carolin, Putke, Kathrin, Schäfer, Gesine, Sauter, Jürgen, Schefzyk, Daniel, Pruschke, Jens, Hofmann, Jan, Fürst, Daniel, Carapito, Raphael, Bahram, Seiamak, Schmidt, Alexander H., Lange, Vinzenz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047279/
https://ncbi.nlm.nih.gov/pubmed/32153595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00314
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