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Allele-Level KIR Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations
The killer-cell immunoglobulin-like receptor (KIR) genes regulate natural killer cell activity, influencing predisposition to immune mediated disease, and affecting hematopoietic stem cell transplantation (HSCT) outcome. Owing to the complexity of the KIR locus, with extensive gene copy number varia...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6288436/ https://ncbi.nlm.nih.gov/pubmed/30564239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02843 |
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