Helicase-like transcription factor-deletion from the tumor microenvironment in a cell line-derived xenograft model of colorectal cancer reprogrammed the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis

Methylation of the HLTF gene in colorectal cancer (CRC) cells occurs more frequently in men than women. Progressive epigenetic silencing of HLTF in tumor cells is accompanied by negligible expression in the tumor microenvironment (TME). Cell line-derived xenografts (CDX) were established in control...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Helmer, Rebecca A., Martinez-Zaguilan, Raul, Kaur, Gurvinder, Smith, Lisa A., Dufour, Jannette M., Chilton, Beverly S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133447/
https://ncbi.nlm.nih.gov/pubmed/34010296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251132
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk