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Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface

Hltf is regulated by intron retention, and global Hltf-deletion causes perinatal lethality from hypoglycemia. In heart, full-length Hltf is a transcriptional regulator of Hif-1α that controls transport systems. Thus, we tested the hypothesis that Hltf deletion from placenta caused or exacerbated neo...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Kaur, Gurvinder, Helmer, Rebecca A., Smith, Lisa A., Martinez-Zaguilan, Raul, Dufour, Jannette M., Chilton, Beverly S.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033450/
https://ncbi.nlm.nih.gov/pubmed/29975766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200211
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