Helicase-Like Transcription Factor (Hltf) Regulates G2/M Transition, Wt1/Gata4/Hif-1a Cardiac Transcription Networks, and Collagen Biogenesis

HLTF/Hltf regulates transcription, remodels chromatin, and coordinates DNA damage repair. Hltf is expressed in mouse brain and heart during embryonic and postnatal development. Silencing Hltf is semilethal. Seventy-four percent of congenic C57BL/6J Hltf knockout mice died, 75% within 12-24 hours of...

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Détails bibliographiques
Auteurs principaux: Helmer, Rebecca A., Martínez-Zaguilán, Raul, Dertien, Janet S., Fulford, Candra, Foreman, Oded, Peiris, Vasum, Chilton, Beverly S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835564/
https://ncbi.nlm.nih.gov/pubmed/24278285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080461
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