Helicase-like transcription factor-deletion from the tumor microenvironment in a cell line-derived xenograft model of colorectal cancer reprogrammed the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis

Methylation of the HLTF gene in colorectal cancer (CRC) cells occurs more frequently in men than women. Progressive epigenetic silencing of HLTF in tumor cells is accompanied by negligible expression in the tumor microenvironment (TME). Cell line-derived xenografts (CDX) were established in control...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Helmer, Rebecca A., Martinez-Zaguilan, Raul, Kaur, Gurvinder, Smith, Lisa A., Dufour, Jannette M., Chilton, Beverly S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2021
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133447/
https://ncbi.nlm.nih.gov/pubmed/34010296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251132
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