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SAT-159 Hltf-Deletion Causes Immune Destruction of Pancreatic Beta Cells during Development

Immune destruction that causes the failure of β cell insulin secretion in type I diabetes (T1D) results from an imbalance in genetic, epigenetic and environmental factors that can begin in utero. A key unanswered question is how and why immune cells are targeted to specifically destroy insulin-produ...

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Détails bibliographiques
Publié dans:J Endocr Soc
Auteurs principaux: Kaur, Gurvinder, Helmer, Rebecca, Dufour, Jannette, Chilton, Beverly
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551699/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-159
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