Integrative chemogenomic analysis identifies small molecules that partially rescue ΔF508‐CFTR for cystic fibrosis

Rare diseases affect 10% of the first‐world population, yet over 95% lack even a single pharmaceutical treatment. In the present age of information, we need ways to leverage our vast data and knowledge to streamline therapeutic development and lessen this gap. Here, we develop and implement an innov...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Hodos, Rachel A., Strub, Matthew D., Ramachandran, Shyam, Meleshkevitch, Ella A., Boudko, Dmitri Y., Bridges, Robert J., Dudley, Joel T., McCray, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129714/
https://ncbi.nlm.nih.gov/pubmed/33934548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12626
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