Integrative chemogenomic analysis identifies small molecules that partially rescue ΔF508‐CFTR for cystic fibrosis

Rare diseases affect 10% of the first‐world population, yet over 95% lack even a single pharmaceutical treatment. In the present age of information, we need ways to leverage our vast data and knowledge to streamline therapeutic development and lessen this gap. Here, we develop and implement an innov...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:CPT Pharmacometrics Syst Pharmacol
Autori principali: Hodos, Rachel A., Strub, Matthew D., Ramachandran, Shyam, Meleshkevitch, Ella A., Boudko, Dmitri Y., Bridges, Robert J., Dudley, Joel T., McCray, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129714/
https://ncbi.nlm.nih.gov/pubmed/33934548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12626
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi