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Evidence against Resveratrol as a viable therapy for the rescue of defective ΔF508 CFTR
BACKGROUND: Resveratrol, a natural phenolic compound, has been reported to rescue mutant ΔF508 CFTR in expression systems and primary epithelial cells. Although this implies a therapeutic benefit to patients with CF, investigations were performed using resveratrol concentrations greatly in excess of...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587346/ https://ncbi.nlm.nih.gov/pubmed/26342647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.08.020 |
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