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ΔF508 CFTR interactome remodeling promotes rescue of Cystic Fibrosis
Deletion of phenylalanine 508 of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the major cause of Cystic Fibrosis (CF), one of the most common inherited childhood diseases. The mutated CFTR anion channel is not fully glycosylated and shows minimal activity in bronchial epithelial...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nature |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826614/ https://ncbi.nlm.nih.gov/pubmed/26618866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15729 |
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