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A post-translational modification code for CFTR maturation is altered in cystic fibrosis
The multistep process regulating the maturation of membrane proteins in the endoplasmic reticulum (ER) and the secretory pathway is disrupted in many protein misfolding disorders. Mutations in the ion channel CFTR that impair its folding and subsequent localization to the plasma membrane cause cysti...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6464640/ https://ncbi.nlm.nih.gov/pubmed/30600261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan7984 |
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