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Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice
The complement system plays a role in the formation of sub-retinal pigment epithelial (RPE) deposits in early stages of age-related macular degeneration (AMD). But the specific mechanisms that connect complement activation and deposit formation in AMD patients are unknown, which limits the developme...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128922/ https://ncbi.nlm.nih.gov/pubmed/34001980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89978-8 |
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