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Deletion of Efemp1 Is Protective Against the Development of Sub-RPE Deposits in Mouse Eyes
PURPOSE: EFEMP1 (fibulin-3) is mutated in Malattia Leventinese/Doyne's honeycomb retinal dystrophy (ML/DHRD), an inherited macular dystrophy similar to AMD. Both ML/DHRD and AMD are characterized by the presence of sub-RPE deposits. Efemp1 knockout mice do not develop sub-RPE deposits. This stu...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5361459/ https://ncbi.nlm.nih.gov/pubmed/28264101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20955 |
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