Risuteganib Protects against Hydroquinone–induced Injury in Human RPE Cells

PURPOSE: Cigarette smoking has been implicated in the pathogenesis of AMD. Integrin dysfunctions have been associated with AMD. Herein, we investigate the effect of risuteganib (RSG), an integrin regulator, on RPE cell injury induced by hydroquinone (HQ), an important oxidant in cigarette smoke. MET...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Yang, Ping, Shao, Zixuan, Besley, Nicholas A., Neal, Samantha E., Buehne, Kristen L., Park, John, Karageozian, Hampar, Karageozian, Vicken, Ryde, Ian T., Meyer, Joel N., Jaffe, Glenn J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
Assuntos:
Retinal Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443126/
https://ncbi.nlm.nih.gov/pubmed/32818234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.10.35
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