Risuteganib Protects against Hydroquinone–induced Injury in Human RPE Cells

PURPOSE: Cigarette smoking has been implicated in the pathogenesis of AMD. Integrin dysfunctions have been associated with AMD. Herein, we investigate the effect of risuteganib (RSG), an integrin regulator, on RPE cell injury induced by hydroquinone (HQ), an important oxidant in cigarette smoke. MET...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Yang, Ping, Shao, Zixuan, Besley, Nicholas A., Neal, Samantha E., Buehne, Kristen L., Park, John, Karageozian, Hampar, Karageozian, Vicken, Ryde, Ian T., Meyer, Joel N., Jaffe, Glenn J.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2020
Matèries:
Retinal Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443126/
https://ncbi.nlm.nih.gov/pubmed/32818234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.10.35
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