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Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells

Purpose. Complement activation is implicated in the pathogenesis of age-related macular degeneration (AMD). Apolipoprotein E (ApoE) and complement activation products such as membrane attack complex (MAC) are present in eyes of individuals with AMD. Herein, we investigated the effect of complement a...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Yang, Ping, Skiba, Nikolai P., Tewkesbury, Grace M., Treboschi, Victoria M., Baciu, Peter, Jaffe, Glenn J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482245/
https://ncbi.nlm.nih.gov/pubmed/28632844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20083
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