On the intrinsic reactivity of highly potent trypanocidal cruzain inhibitors

The cysteine protease cruzipain is considered to be a validated target for therapeutic intervention in the treatment of Chagas disease. Hence, peptidomimetic cruzipain inhibitors having a reactive group (known as warhead) are subject to continuous studies to discover novel antichagasic compounds. He...

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Detaylı Bibliyografya
Yayımlandı:RSC Med Chem
Asıl Yazarlar: Bonatto, Vinicius, Batista, Pedro Henrique Jatai, Cianni, Lorenzo, De Vita, Daniela, Silva, Daniel G., Cedron, Rodrigo, Tezuka, Daiane Y., de Albuquerque, Sérgio, Moraes, Carolina Borsoi, Franco, Caio Haddad, Lameira, Jerônimo, Leitão, Andrei, Montanari, Carlos A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: RSC 2020
Konular:
Chemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126975/
https://ncbi.nlm.nih.gov/pubmed/34095840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00097c
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