Caricamento...

Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper‐resection

The Mec1/ATR kinase is crucial for genome maintenance in response to a range of genotoxic insults, but it remains unclear how it promotes context‐dependent signaling and DNA repair. Using phosphoproteomic analyses, we uncovered a distinctive Mec1/ATR signaling response triggered by extensive nucleol...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Sanford, Ethan J, Comstock, William J, Faça, Vitor M, Vega, Stephanie C, Gnügge, Robert, Symington, Lorraine S, Smolka, Marcus B
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126923/
https://ncbi.nlm.nih.gov/pubmed/33764556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104566
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !