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Phosphoproteomics Reveals Distinct Modes of Mec1/ATR Signaling During DNA Replication
The Mec1/Tel1 kinases (human ATR/ATM) play numerous roles in the DNA replication stress response. Despite the multi-functionality of these kinases, studies of their in vivo action have mostly relied on a few well-established substrates. Here we employed a combined genetic-phosphoproteomic approach t...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369404/ https://ncbi.nlm.nih.gov/pubmed/25752575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.01.043 |
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