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Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling
The Mec1/ATR kinase coordinates multiple cellular responses to replication stress. In addition to its canonical role in activating the checkpoint kinase Rad53, Mec1 also plays checkpoint-independent roles in genome maintenance that are not well understood. Here we used a combined genetic–phosphoprot...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Genes Dev |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cold Spring Harbor Laboratory Press
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049512/ https://ncbi.nlm.nih.gov/pubmed/29899143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.308148.117 |
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