DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells

Rationale: Dysregulation of the PI3K/AKT/mTOR pathway occurs frequently in cancers, providing an attractive therapeutic target for anticancer treatments. DEPTOR plays essential roles in regulation of cell proliferation and survival by directly modulating mTOR activity. However, whether DEPTOR regula...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Bi, Yanli, Chen, Xiaoyu, Wei, Bajin, Wang, Linchen, Gong, Longyuan, Li, Haomin, Xiong, Xiufang, Zhao, Yongchao
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120212/
https://ncbi.nlm.nih.gov/pubmed/33995662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51286
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