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Nuclear ErbB2 represses DEPTOR transcription to inhibit autophagy in breast cancer cells

ErbB2, a classical receptor tyrosine kinase, is frequently overexpressed in breast cancer cells. Although the role of ErbB2 in the transmission of extracellular signals to intracellular matrix has been widely studied, the functions of nuclear ErbB2 remain largely elusive. Here, we report a novel fun...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Bi, Yanli, Gong, Longyuan, Liu, Pengyuan, Xiong, Xiufang, Zhao, Yongchao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047043/
https://ncbi.nlm.nih.gov/pubmed/33854045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03686-9
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