DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells

Rationale: Dysregulation of the PI3K/AKT/mTOR pathway occurs frequently in cancers, providing an attractive therapeutic target for anticancer treatments. DEPTOR plays essential roles in regulation of cell proliferation and survival by directly modulating mTOR activity. However, whether DEPTOR regula...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Bi, Yanli, Chen, Xiaoyu, Wei, Bajin, Wang, Linchen, Gong, Longyuan, Li, Haomin, Xiong, Xiufang, Zhao, Yongchao
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120212/
https://ncbi.nlm.nih.gov/pubmed/33995662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51286
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