Oncogenic Extrachromosomal DNA Functions as Mobile Enhancers to Globally Amplify Chromosomal Transcription

Extrachromosomal, circular DNA (ecDNA) is emerging as a prevalent, yet less characterized oncogenic alteration in cancer genomes. We leverage ChIA-PET and ChIA-Drop chromatin interaction assays to characterize genome-wide ecDNA-mediated chromatin contacts that impact transcriptional programs in canc...

全面介紹

Na minha lista:
書目詳細資料
發表在:Cancer Cell
Main Authors: Zhu, Yanfen, Gujar, Amit D., Wong, Chee-Hong, Tjong, Harianto, Ngan, Chew Yee, Gong, Liang, Chen, Yi-An, Kim, Hoon, Liu, Jihe, Li, Meihong, Mil-Homens, Adam, Maurya, Rahul, Kuhlberg, Chris, Sun, Fanyue, Yi, Eunhee, deCarvalho, Ana C., Ruan, Yijun, Verhaak, Roel G.W., Wei, Chia-Lin
格式: Artigo
語言:Inglês
出版: 2021
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119378/
https://ncbi.nlm.nih.gov/pubmed/33836152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2021.03.006
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍