ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation

Activation of the epidermal growth factor receptor (EGFR) is crucial for development, tissue homeostasis, and immunity. Dysregulation of EGFR signaling is associated with numerous diseases. EGFR ubiquitination and endosomal trafficking are key events that regulate the termination of EGFR signaling,...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Shen, Chia-Hsing, Chou, Chih-Chang, Lai, Ting-Yu, Hsu, Jer-En, Lin, You-Sheng, Liu, Huai-Yu, Chen, Yan-Kai, Ho, I-Lin, Hsu, Pang-Hung, Chuang, Tsung-Hsien, Lee, Chih-Yuan, Hsu, Li-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118649/
https://ncbi.nlm.nih.gov/pubmed/33996800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.642625
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