ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation

Activation of the epidermal growth factor receptor (EGFR) is crucial for development, tissue homeostasis, and immunity. Dysregulation of EGFR signaling is associated with numerous diseases. EGFR ubiquitination and endosomal trafficking are key events that regulate the termination of EGFR signaling,...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Shen, Chia-Hsing, Chou, Chih-Chang, Lai, Ting-Yu, Hsu, Jer-En, Lin, You-Sheng, Liu, Huai-Yu, Chen, Yan-Kai, Ho, I-Lin, Hsu, Pang-Hung, Chuang, Tsung-Hsien, Lee, Chih-Yuan, Hsu, Li-Chung
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118649/
https://ncbi.nlm.nih.gov/pubmed/33996800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.642625
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