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Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking

The transmembrane prostate androgen-induced protein (TMEPAI) has been reported to be elevated in various tumor cells, is localized to the lysosome and promotes lysosome stability. The molecular mechanism of TMEPAI trafficking however to the lysosome is unknown. Here we report that clathrin and CI-M6...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Luo, Shenheng, Jing, Lei, Zhao, Tian, Li, Yuyin, Liu, Zhenxing, Diao, Aipo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316989/
https://ncbi.nlm.nih.gov/pubmed/28218281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42668
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