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Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking

The transmembrane prostate androgen-induced protein (TMEPAI) has been reported to be elevated in various tumor cells, is localized to the lysosome and promotes lysosome stability. The molecular mechanism of TMEPAI trafficking however to the lysosome is unknown. Here we report that clathrin and CI-M6...

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Publicat a:Sci Rep
Autors principals: Luo, Shenheng, Jing, Lei, Zhao, Tian, Li, Yuyin, Liu, Zhenxing, Diao, Aipo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316989/
https://ncbi.nlm.nih.gov/pubmed/28218281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42668
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