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Regulation of Epidermal Growth Factor Receptor Ubiquitination and Trafficking by the USP8·STAM Complex

Reversible ubiquitination of activated receptor complexes signals their sorting between recycling and degradation and thereby dictates receptor fate. The deubiquitinating enzyme ubiquitin-specific protease 8 (USP8/UBPy) has been previously implicated in the regulation of the epidermal growth factor...

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Autores principales: Berlin, Ilana, Schwartz, Heather, Nash, Piers D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966105/
https://ncbi.nlm.nih.gov/pubmed/20736164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016287
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