Chargement en cours...
Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome
Inflammasomes are filamentous signaling platforms integral to innate immunity. Currently, little is known about how these structurally similar filaments recognize and distinguish one another. A cryo-EM structure of the AIM2(PYD) filament reveals that the architecture of the upstream filament is esse...
Enregistré dans:
| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8115694/ https://ncbi.nlm.nih.gov/pubmed/33980849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23045-8 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|