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Digital signaling network drives the assembly of the AIM2-ASC inflammasome

The AIM2-ASC inflammasome is a filamentous signaling platform essential for mounting host defense against cytoplasmic dsDNA arising not only from invading pathogens but also from damaged organelles. Currently, the design principles of its underlying signaling network remain poorly understood at the...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Matyszewski, Mariusz, Morrone, Seamus R., Sohn, Jungsan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834677/
https://ncbi.nlm.nih.gov/pubmed/29440442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712860115
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