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Digital signaling network drives the assembly of the AIM2-ASC inflammasome
The AIM2-ASC inflammasome is a filamentous signaling platform essential for mounting host defense against cytoplasmic dsDNA arising not only from invading pathogens but also from damaged organelles. Currently, the design principles of its underlying signaling network remain poorly understood at the...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834677/ https://ncbi.nlm.nih.gov/pubmed/29440442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712860115 |
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