The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study

JNJ-42165279 is a selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for the degradation of fatty acid amides (FAA) including anandamide (AEA), palmitoylethanolamide (PEA), and N-oleoylethanolamide (OEA). We assessed the efficacy, safety, tolerability, pharmacokinetics,...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Schmidt, Mark E., Liebowitz, Michael R., Stein, Murray B., Grunfeld, Jennifer, Van Hove, Ilse, Simmons, W. Kyle, Van Der Ark, Peter, Palmer, James A., Saad, Ziad S., Pemberton, Darrel J., Van Nueten, Luc, Drevets, Wayne C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115178/
https://ncbi.nlm.nih.gov/pubmed/33070154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-00888-1
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