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α-Ketoheterocycle-Based Inhibitors of Fatty Acid Amide Hydrolase (FAAH)

[Image: see text] A summary of the initial discovery and characterization of the enzyme fatty acid amide hydrolase (FAAH), and the subsequent advancement of an important class of competitive, reversible, potent, and selective inhibitors is presented. Initially explored using substrate-inspired inhib...

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Bibliografiske detaljer
Main Authors: Otrubova, Katerina, Boger, Dale L.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359644/
https://ncbi.nlm.nih.gov/pubmed/22639704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2001206
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