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α-Ketoheterocycle-Based Inhibitors of Fatty Acid Amide Hydrolase (FAAH)

[Image: see text] A summary of the initial discovery and characterization of the enzyme fatty acid amide hydrolase (FAAH), and the subsequent advancement of an important class of competitive, reversible, potent, and selective inhibitors is presented. Initially explored using substrate-inspired inhib...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Otrubova, Katerina, Boger, Dale L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2011
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359644/
https://ncbi.nlm.nih.gov/pubmed/22639704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2001206
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