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A metallo-β-lactamase enzyme for internal detoxification of the antibiotic thienamycin
Thienamycin, the first representative of carbapenem antibiotics was discovered in the mid-1970s from soil microorganism, Streptomyces cattleya, during the race to discover inhibitors of bacterial peptidoglycan synthesis. Chemically modified into imipenem (N-formimidoyl thienamycin), now one of the m...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8115136/ https://ncbi.nlm.nih.gov/pubmed/33980996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89600-x |
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